Cartilage lesions of the knee treated with blood mesenchymal stem cells – results. Jan Skowroński , Marcin Rutka, Rafał Skowroński Ortop Traumatol Rehabil 2012; 14(6):569-577 ICID: 1012404
Article type: Original article
IC™ Value: 3.00
Abstract provided by Publisher
The study aimed to assess long-term clinical outcomes of cartilage lesion treatment with blood stem cells. The analysis of complications of this method was an additional aim.
The study group comprised 52 patients with ICRS grade III or IV lesions of 4 to 12 cm2. The assessment was carried out at one and six years following the surgery with the use of KOOS and Lysholm scales and VAS and KOOS Pain scales.
No postoperative infections were reported. Poor outcomes were noted in 2 patients at 12 months following the surgery. Scores improved in across all scales with an average improvement of 23 points in the KOOS scale and 35 points in the Lysholm scale at one year. At 6 years, minor deterioration was reported in 2 more patients.
1) The reconstruction of large cartilage lesions with peripheral blood stem cells is an effective treatment modality.
2) This method is a valuable alternative to autologous chondrocyte transplantation.
DOI 10.5604/15093492.1012404 PMID 23382284 - click here to show this article in PubMed