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Journal Abstract
 
Mechanical properties of subchondral bone in degenerative joint disease
Dariusz Chmielewski
Ortop Traumatol Rehabil 2002; 4(5):639-641
ICID: 16262
Article type: Review article
IC™ Value: 4.68
Abstract provided by Publisher
 
Analysis of the role which subchondral bone plays in etiopathogenesis of the arthrotic joint diseases continues for a long time. Introduction of the new imaging techniques helps to evaluate those changes clearly. The work is a presentation of the current views on correlation between changes in bone and overlaying articular surfaces in consideration with potential possibilities of therapeutic intervention. It also contains a discussion on the Ball'a theory from 1966, who thought that osteoarthrosis protects against osteoporosis. Actually, it's well known, that both processes coexists and could be correlated. Kaneko's theories presented in this paper, helps to evaluate the role of inflammatory cytokines and proteinases in subchondral destruction and arthrosis. Probably in this field we can find the possible way to modify this process in modern therapies.

ICID 16262
PMID 17992175 - click here to show this article in PubMed


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