Archival Issues
Volume 19, 2017
Volume 18, 2016
Volume 17, 2015
Volume 16, 2014
Volume 15, 2013
Volume 14, 2012
Volume 13, 2011
Volume 12, 2010
Volume 11, 2009
Volume 10, 2008
Volume 9, 2007
Volume 8, 2006
Volume 7, 2005
Volume 6, 2004
Volume 5, 2003
Volume 4, 2002
Volume 3, 2001
Volume 2, 2000
Volume 1, 1999
Journal Abstract
The effect of antibiotic therapy on the incidence of Staphylococcus aureus infections
Joanna Dzwonkowska , Julianna Kurlenda , Bogusław Baczkowski , Stanisław Mazurkiewicz , Ivelin Uzunov , Włodzimierz Ziółkowski , Agnieszka Markowicz
Ortop Traumatol Rehabil 2007; 9(5):532-547
ICID: 538768
Article type: Original article
IC™ Value: 7.12
Abstract provided by Publisher
This paper reports on aetiological factors, including mostly S. aureus infections, and antibiotic use in the pretreatment and treatment of complicating infections in patients hospitalised at the Department of Orthopaedics and Musculoskeletal Traumatology, Gdańsk Medical University, between 1995 and 2004.
The analysis sought to establish a correlation, via statistical analysis, between the usage of specific antibiotic classes, with special regard to lincosamides, and S. aureus infection rates.The study population included 22,686 patients admitted for elective surgery (accounting for 86.9% to 75.1% of the sample in different years) or with acute injuries.The rate of infections ranged from 2.79% to 1%, decreasing in a statistically significant manner over time. S. aureus was the dominant pathogen, accounting for 67.3% to 27.6% of the total number of bacterial strains. During the time frame of the study, the incidence of osteitis fell considerably, from 0.8% to 0.05% of the total number of patients. This was paralleled by a major increase in the use of lincosamides, mostly clindamycin. The increase in lincosamide use correlated with the decreasing incidence of S. aureus infections.The statistical outcome of this 10-year study has been used to develop schemes of antibiotic therapy in the Department, a necessary component of the Hospital’s economic policy at the moment.A major fall in the incidence of nosocomial infections can be achieved by focussing on adequate antibiotic prophylaxis, pretreatment and appropriate treatment of acute infections.

ICID 538768
PMID 18026073 - click here to show this article in PubMed

Related articles
  • in IndexCopernicus™
         Osteitis [43 related records]
         orthopaedics [10 related records]
         Staphylococcus aureus [256 related records]
         Infection [256 related records]

  • Related articlesin PubMed database
  • in PubMed database [ related records]


    Copyright © Ortopedia Traumatologia Rehabilitacja  2017
    Page created by Index Copernicus Ltd. All Rights reserved.